백서에서 Carbamide peroxide bleaching gel이 치수 및 치주조직에 미치는 영향
THE EFFECT OF CARBAMIDE PEROXIDE BLEACHING GEL ON DENTAL PULP AND PERIODONTAL TISSUE IN RATS
김선호, 김민석, 김선헌, 김부길, 기우천,
소속 상세정보
김선호 ( ) - 전남대학교 치과대학 보존학교실
김민석 ( ) - 전남대학교 치과대학 구강해부학교실
김선헌 ( ) - 전남대학교 치과대학 구강해부학교실
김부길 ( ) - 전남대학교 치과대학 보존학교실
기우천 ( ) - 전남대학교 치과대학 보존학교실
KMID : 0362320000250020289
Abstract
Carbamide peroxide is usually used for vital teeth bleaching at home. Complications such as tooth hyperensitivity and/or gingival irritation are frequently reported. Therefore, this study was performed to evaluate any possible histological changes in pulp and periodontal tissue by carbamide peroxide bleaching gel in rats.
10% and 15% carbamide peroxide containing nightguard for upper molar were worn for 4 hours a day. The rats were sacrificed after 1 day. 2 days. 3 days. 4 days and 6 days application of carbamide peroxide respectively.
The results were as follows:
Mild infiltration of inflammatory changes below the junctional epithelium and hyperplasia of epithelium were observed in both 10% and 15% carbamide peroxide treated groups.
In all experimental groups, odontoblasts were changed from columnar to cuboidal shape and/or obliterated and the focal loss of predentin was observed in pulp horn. With increasing time of application, these changes were more remarkable, but limited in pulp horn.
Inflammatory reactions, vacuolar changes and hyaline degenerations of the pup tissue were also observed in some cases.
These results suggested that carbamide peroxide gel used in home bleaching could cause reversible pulpal irritation.
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